We don’t just make smoothies, we make mood fuel.

Serotonin Smoothies was born in the heart of the Lower East Side, a neighborhood known for its energy, grit, and creativity. Living here, balance felt essential — the kind of balance between long days and late nights, work and play, health and comfort.

That’s where the idea for the shop came from: a place where you don’t have to choose between a smoothie packed with superfoods and the simple joy of a bacon, egg & cheese. Where a chicken Caesar wrap sits right next to a sea moss–powered blend, and a smashburger can share the table with a protein shake.

We built Serotonin Smoothies with that understanding of balance — because fueling your body and feeding your soul should go hand in hand. Our mission is simple: to serve drinks that lift your energy and support your health, to make food that feels like home, and to create a vibe that leaves everyone walking out the door better than they came in. This shop is more than a menu — it’s a reflection of the LES spirit: bold, authentic, and full of flavor.

About the owner

Sarah Romeu is the proud founder and owner of this little haven nestled in the bustling streets of Lower East Side.

As a lifelong enthusiast of wellness and holistic practices, Sarah has always believed in the transformative power of nourishing and delicious food. It was this deep-rooted belief that fueled her journey from a humble blender in her kitchen to opening up Serotonin Smoothies to share her vision with NYC. Our eclectic menu features organic ingredients sourced to perfection and our warm, welcoming ambiance embraces everyone who walks through our doors.

Sarah’s mission with Serotonin Smoothies goes beyond just serving delicious drinks; it's about fostering a sense of connection and well-being within our community. Whether you're a fitness fanatic seeking a post-workout boost, a busy professional in need of a nutritious pick-me-up, or a family looking for a wholesome treat, there's something for everyone at our shop. Serotonin Smoothies is a testament to the power of female entrepreneurship. As a woman-owned business, Sarah is incredibly proud to be a part of the vibrant tapestry of female-led ventures shaping the landscape of NYC. She is passionate about empowering other women to pursue their dreams and carve out their own paths, just as she has.

So, whether you're a long-time regular or a curious passerby, we invite you to join us at Serotonin Smoothies and experience the blend of flavors, creativity, and community that make us more than just a smoothie shop — we're a destination for nourishment and inspiration…Come sip with us!